Defining the normal range ofα -tocopherol for pregnant women

Pregnant women are under the risk of developing pre-eclampsia. Some studies indicate that women with pre-eclampsia have higher values of isoprostanes, which includes α -and γ -tocopherol, compared to women without pre-eclampsia. To be able to predict whether the pregnant women have the danger of pre-eclampsia or not, it is important to know the normal values of α -and γ -tocopherol. In my paper, I concentrate on α -tocopherol and based on a sample of 52 women, estimate the normal range for pregnant women without pre-eclampsia. With the normal range, we can identify the women with high values. In order to estimate the values of each week, we derived a model that describes the percentiles as a function of the time (weeks) during the gestational period was estimated. Through the parametric and non-parametric methods, the percentiles for each observed week were computed. The percentile curves were derived basing on the percentile estimates. Also use mean and sd method to estimate percentiles as another method. We can estimate the α -tocopherol of specific weeks through the function.